The Science Behind Building Youthful Cells

What is Redox? The Science Behind Cellular Healing. The Science Behind Building Youthful Cells

In a country with some of the most advanced science in the world, we also face some of the highest disease rates. The old paradigm of treating symptoms is no longer cutting it, and a population of natural health hunters is emerging.



As new bodily mechanisms are being discovered and understood, our notion of healthcare is transforming as well. Concepts like redox are proving to be profound in addressing the root cause of illness and supporting health and longevity. Today we will explore redox science, and how you can use redox signaling molecules to transform your health for the better.

Modern Healthcare: It’s Time For Change

Our modern healthcare system is notorious for prescribing pharmaceutical medications to manage the symptoms of the disease. In doing so, we aren’t addressing the root cause. These drugs come with a host of side effects, which are then “treated” with more pharmaceuticals. This catch 22 can continue on indefinitely without ever truly healing the individual.

Treating the root causes of a disease requires a much more profound understanding of our natural human biology. One such discovery is that of redox, a signaling process that is involved with a wide range of biological processes from inflammation to cancer. By harnessing the wisdom of redox science, we can start to address the root causes of modern disease, and give the body the building blocks it needs to heal itself.

The Science behind Redox

What is redox? Redox refers to the loss or gain of electrons through reduction and oxidation. Redox signaling occurs when specific molecules like free radicals, reactive oxygen species, and other compounds influence the body and are like a warning sign that cells give one another.

These signals allow cells to detect damage, protect themselves, and repair or replace injured cells.

Redox molecules are made by mitochondria using the solution that they themselves exist in– saline. Indeed, your cells contain saltwater, and your mitochondria use this sodium, chloride, hydrogen, and oxygen solution to generate redox signaling molecules. These highly reactive molecules then go to work or are converted back into salt water to be used again at a later date.

Redox Signaling Molecules And Cell Signaling

The body’s cells are like factories that generate fuel, or ATP, to power the body. ATP is created by the mitochondria within the cells, and these mitochondria are also responsible for intracellular communication. Cell signaling is vital for health because it ensures things like immune function, tissue repair, cell development, hormone operations, and essentially every single bodily process.

Inside the cell, mitochondria create these redox signaling molecules which enable communication between one another. Redox signals are like the language of cells, without them there would be no life as we know it. In fact, when our cells fail to communicate clearly with one another, autoimmune conditions become much more likely. Cells fail to distinguish between good and bad cells– the body accidentally begins to attack itself.

Redox Signaling Molecules And Age

These redox signaling molecules are made by the trillions daily by mitochondria inside of the cell, but these numbers start to drop significantly with age. This is due partially to the fact that our mitochondria lessen with age. They die off naturally, and this happens faster with trauma (injury) and due to toxicity.

The irony here, of course, is that those with the least amount of mitochondria due to illness and toxicity, are the ones who need them most. We progressively have fewer mitochondria to make the redox signaling molecules. Therefore, the mitochondria that we do have work much less efficiently as we grow older.

On average, there is a 10% reduction in mitochondria and redox molecules per decade once someone has gone through puberty. This number is staggering and highlights the importance of optimizing redox potential as soon as possible.

This reduction of redox signaling molecules impacts our bodies in many ways. One obvious example is the body’s ability to heal slows with age. A bruise that may last a couple of days for a child might last a couple of weeks or months in an elderly person.

Healing from the common flu as a teenager could last much longer, and become much more severe in an elderly person. Less redox signaling molecules = less communication between cells = longer periods to repair tissues and cells, and longer periods of immune recovery.
Higher Redox Potential, Better Health

Ultimately, the higher your redox potential, the healthier you will be. Redox potential is a strong indicator not only of health but also of longevity. This mechanism influences such a wide range of bodily functions.

A high redox potential enables your body to heal damaged cells and create new ones, and it also plays a role in supporting your natural detoxification pathways as well as your immune function.

Redox signaling molecules help your body to clear out toxins like heavy metals and BPA’s. Redox signaling also supports your immune system to fight off any exposure to pathogens, bacteria, and viruses. It’s the ultimate player for healing as well as preventative healthcare.

Good health is a balancing act between avoiding exposure to harmful elements while also being strong enough to overcome the exposures that we inevitably come in contact with. Even if you’re living in a pristine forest away from any modern pollution or toxins.

Your body will require redox signaling molecules anytime you get injured or sick. As we age, these molecules become less available. Taking actions to boost your redox potential becomes especially important as you get older.

Being mindful of redox potential is an integral part of living a healthy lifestyle. Support your mitochondria at the cellular level by boosting its redox potential. This will magnify all the other efforts you make when it comes to a healthy diet, exercise, and rest. Give your body the building blocks to build these redox signaling molecules.

Your mitochondria can continue to generate them, and support your health today and for years to come.

Why You Need To Know About Redox Signaling Molecules

Although not a likely dinner topic, life happens deep within our cellular mitochondria with chemical reactions known as redox signaling. Learn why redox imbalances are responsible for every illness from diabetes to cancer.

They call them Redox Signaling Molecules. The National Institute of Health (NIH), Stanford, Harvard, Cornell, and many other top medical research institutions are utilizing huge sums of money and dedicating entire labs toward studying these tiny molecules, after finding they are a cornerstone to preventing disease.

Our bodies are made up of cells. Inside of every cell we have mitochondria (some cells have thousands). When functioning optimally, mitochondria produce redox signaling molecules called Reactive Oxygen Species (ROS). The ROS molecules fall into two categories: reductants that cause reduction reactions or oxidants that create oxidation reactions.

Redox signaling processes take place in nature every time there is a chemical reaction, including inside our cells. Both reductants and oxidants are important, and in order to maintain optimal health, we require them in balanced numbers.

Oxidants remove electrons; when they are exposed to oxygen they oxidize and change color—think rust on a nail or an apple turning brown.

Reductants deliver electrons. One of the most important redox signaling process that takes place in the mitochondria is with the addition of electrons to oxygen molecules.

A Matter Of Balance

Our cells require balance or for peak performance. When there is a buildup of oxidants in our cells or disequilibrium inside the cell this notifies us of damage and a poorly functioning cell. The buildup of oxidants is called .

The redox signaling process can be likened to smoke signals. Oxidants inside our cells can go rogue and result in major health damage if they aren’t cleaned up and controlled. The overabundance of oxidants in cells are the mechanism that tells the cell something is wrong and initiates the process where the body begins to repair, kill, or replace the cell.

When there are too many oxidants in the cell, it signals the genes inside of the nucleus to fix the problem. Hopefully, the action from the genes will fix the problem and homeostatic balance will be restored again inside the cell—this is the redox signaling process. This process is of the utmost importance for detection of damaged cells, as well as repair, and replacement of damaged cells inside of tissue.

Redox imbalances have been correlated with every single disease including aging, Alzheimer’s, atherosclerosis, diabetes, , cancer, dementia, ALS, chronic infections, gut disorders, arthritis, and more.

“All illness is expressed in one of two ways: a predominance of oxidative stress-related symptoms and signs (similar to rusting, but in a biological sense), or a predominance of (reactive) signs and symptoms. Health can be achieved by addressing imbalances in these areas and then moving the redox needle back to the balance point,” writes Robertson D. Ward, M.D. FAAFP.

Recently, the scientist who discovered the DNA double helix, James Watson, announced that redox signaling is the cause of diabetes. Consequently, he’s dedicated the remainder of his life’s research to redox research.
Redox Signaling Key To Cell Repair

In order to understand the importance of redox signaling, we need to have a clear understanding of the metabolic process and some basic terms:

Free radicals form when a group of atoms, having an odd number of electrons, (resulting in one or more unpaired electrons) interact with oxygen. While this can be a bewildering idea, it’s true, our bodies rely on oxygen in order to survive. However, if not balanced by supplements or the body’s own antioxidant mechanisms, this oxygenation process is also expensive to our health and contributes to disease, aging, and deterioration.

Oxidative damage occurs when these unstable free radicals interact with other molecules in the body. As these unstable reactive radicals domino, one unstable molecule steals an electron from the next and so on. This results in a snowball effect and creating imbalance in reductants and oxidants greater than the body is able to remedy or mitigate.

The deleterious effects of oxidative damage affect DNA and cell function. Cells may function poorly or die if this occurs. To prevent free radical damage the body must deploy its defense system of antioxidants including , Super Oxide Dismutase (SOD), and Catalase, or utilize external supplemental sources of antioxidants. Redox signaling supplements can increase our body’s production of these endogenously produced antioxidants.

Antioxidants are molecules which can safely interact with free radicals and terminate the chain reaction before vital molecules are damaged. work by reducing oxidants into their reduced form through donating electrons without becoming free radicals themselves.

Reduction is a type of redox signaling reaction. Every time molecules are reduced, they change shape and function. This is good news for our bodies. As the oxidative stress in our bodies is balanced, either through natural processes or with proper supplementation, remediation and recycling can occur in the following imperative areas: repairing damaged molecules including DNA, chelating or removing toxic metals, increasing natural endogenous production of antioxidants, enhancing protection from free radicals, or promoing apoptosis (death of cancerous or mutated cells).

Each person’s cell redox potential affects the whole mechanism of every cell in the body including the expression of genes. When redox signaling is operating well, genes then express the molecules that are necessary to restore the homeostatic balance that are either replacing, recycling, or repairing the cell. This homeostatic restoration balance takes place through redox signaling. Plainly put, if our redox signaling molecules are not functioning optimally, our genes cannot function optimally.

The importance of this cannot be overstated: redox signaling processes in the cells are the fundamental processes by which the cell detects damage and then start the repair and replace mechanisms taking place in the mitochondria, including autophagy and apoptosis.

Apoptosis is a process of cell death also referred to as cell suicide. Apoptosis should begin only two hours following detection of too high levels of oxidants in the cell. In , apoptosis does not occur, allowing cancer cells to become immortal. The cells are unable to detect damage and unable to repair themselves.

In this case, the mitochondria have broken down as a result of their lost ability to carry on the network of redox signaling, impairing the apoptosis process from taking place. When a cancer cell goes rogue it continues to replicate itself and spreads to other parts of the body leading to death.

Autophagy is the single pathway to remove and recycle older mitochondria that are broken. This process removes poor functioning mitochondria without killing the cell. This process occurs most often during sleep. Autophagy has been of major interest to the Paleo and biohacking communities in recent years as we are learning of various supplements, lifestyle changes, and dietary changes that have the ability to increase autophagy, and improve redox potential and mitochondrial health.

Some of the most popular tools include implementing proper , use of Asea, and other supplements, including dietary tools such as , blocking the blue light spectrum, and cryotherapy.

With regard to chronic infection and chronic disease, , bacteria, and parasites thrive in bodies that have compromised mitochondrial function.

We now know the redox signaling messengers inside the mitochondria are the place where life happens—after more than 17 years of clinical trials and millions of dollars spent, we are just beginning to connect the dots in this ever expanding exploration of redox signaling, disease, and wellness.

Boost Redox Potential with ASEA

Redox Signal Molecules are made inside your cells and are foundational to ALL cellular health. But your body begins to make less of these vital molecules as you are exposed to toxins, mental and physical stresses, and health challenges. In fact, even if we lived in a perfectly pristine, stress-free world, the simple act of aging past 20 decreases your body’s ability to make these molecules by approximately 10% every decade.

Science said there was nothing you could do about it – until now! ASEA, sometimes called ASEA Water, is the ONLY supplement in the world to contain stabilized Redox Signaling Molecules. After almost two decades, millions of dollars of research and multiple patents, the scientists behind ASEA achieved what the scientific community said was impossible!

Starting with nothing more than salt and water (similar to what is found inside your cells) and passing it through a complex three-day process, ASEA creates stabilized Redox Signaling Molecules outside of the body. There are only two places where you can find these vital molecules – inside every living organism and inside a bottle of ASEA.

References:

Adler, Victor, Zhimin Yin, Kenneth D. Tew, and Zeev Ronai. “Role of Redox Potential and Reactive Oxygen Species in Stress Signaling.” Oncogene18, no. 45 (1999): 6104-111. doi:10.1038/sj.onc.1203128.

Cheeseman, KH, and TF Slater. “An Introduction to Free Radical Biochemistry.” Oxford Academic 49, no. 3, 481-93. doi:10.1093/oxfordjournals.bmb.a072625.

Hancock, John, and Matthew Whiteman. “Cellular Redox Environment and Its Influence on Redox Signaling Molecules.” Reactive Oxygen Species, 2018. doi:10.20455/ros.2018.815.

Lobo, V., A. Patil, A. Phatak, and N. Chandra. “Free Radicals, Antioxidants and Functional Foods: Impact on Human Health.” Pharmacognosy Reviews4, no. 8 (2010): 118. doi:10.4103/0973-7847.70902.

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